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Publications

Our scientific output and findings

From groundbreaking discoveries in basic science to innovative clinical insights, our publications showcase the breadth and depth of research taking place at the UK DRI. 

Alzheimer's & dementia (Amsterdam, Netherlands)
Published

Online46: Online cognitive assessments in elderly cohorts-The British 1946 birth cohort case study

Authors
Ziyuan Cai, Valentina Giunchiglia, Rebecca Street, Martina Del Giovane, Kirsty Lu, Maria Popham, Andrew Wong, Heidi Murray-Smith, Marcus Richards, Sebastian Crutch, Peter J Hellyer, Jonathan M Schott, Adam Hampshire
Online46: Online cognitive assessments in elderly cohorts-The British 1946 birth cohort case study
Infectious diseases (London, England)
Published

Increased immune activation in people living with HIV on antiretroviral therapy but not when compared with persons on HIV preexposure prophylaxis

Authors
Josefina Robertson, Arvid Edén, Aylin Yilmaz, Lars-Magnus Andersson, Lars Hagberg, Kristina Nyström, Staffan Nilsson, Carl-Johan Treutiger, Petra Tunbäck, Johanna M Gostner, Henrik Zetterberg, Magnus Gisslén
Increased immune activation in people living with HIV on antiretroviral therapy but not when compared with persons on HIV preexposure prophylaxis
Med (New York, N.Y.)
Published

Longitudinal progression of blood biomarkers reveals a key role of reactive astrocytosis in preclinical Alzheimer's disease

Authors
Vijay R Varma, Yang An, Przemek R Kac, Murat Bilgel, Abhay Moghekar, Tina Loeffler, David Amschl, Magdalena Daurer, Manuela Prokesch, Juan Troncoso, Kaj Blennow, Henrik Zetterberg, Nicholas J Ashton, Luigi Ferrucci, Susan M Resnick, Madhav Thambisetty
Longitudinal progression of blood biomarkers reveals a key role of reactive astrocytosis in preclinical Alzheimer's disease
Alzheimer's & dementia : the journal of the Alzheimer's Association
Published

Cerebrospinal fluid and brain positron emission tomography measures of synaptic vesicle glycoprotein 2A: Biomarkers of synaptic density in Alzheimer's disease

Authors
Adam P Mecca, Nicholas J Ashton, Ming-Kai Chen, Ryan S O'Dell, Takaya Toyonaga, Wenzhen Zhao, Juan J Young, Elaheh Salardini, Kara A Bates, Jocelyn Ra, Sam Goodcase, Jason A Silva-Rudberg, Nabeel B Nabulsi, Ann Brinkmalm, Hlin Kvartsberg, Michael Schöll, Johanna Nilsson, Amy F T Arnsten, Yiyun Huang, Oskar Hansson, Henrik Zetterberg, Richard E Carson, Kaj Blennow, Christopher H van Dyck
Cerebrospinal fluid and brain positron emission tomography measures of synaptic vesicle glycoprotein 2A: Biomarkers of synaptic density in Alzheimer's disease
Movement disorders : official journal of the Movement Disorder Society
Published

Brain Networks Route Neurodegeneration Patterns in Patients with Progressive Supranuclear Palsy

Authors
Carla Palleis, Andrea Quattrone, Amir Dehsarvi, Sebastian N Roemer-Cassiano, Alexander M Bernhardt, AL‐108‐231 Investigators, the PASSPORT Study Group, Hans-Jürgen Huppertz, Maura Malpetti, Adam L Boxer, Johannes Gnörich, Lukas Frontzkowski, Johannes Levin, Matthias Brendel, Günter U Höglinger, Nicolai Franzmeier
Brain Networks Route Neurodegeneration Patterns in Patients with Progressive Supranuclear Palsy
Brain : a journal of neurology
Published

Misdirected yet intact TREX1 exonuclease activity causes human cerebral and systemic small vessel disease

Authors
Sarah McGlasson, Katy Reid, Anna Klingseisen, Bastien Rioux, Samuel Chauvin, Cathrine A Miner, Joe Holley, Deborah Forbes, Bethany Geary, Jeffrey Kimber, Katrina Wood, Candice Roufosse, Colin Smith, David Kavanagh, Jonathan Miner, David P J Hunt
Misdirected yet intact TREX1 exonuclease activity causes human cerebral and systemic small vessel disease
The journal of prevention of Alzheimer's disease
Published

Utility of plasma GFAP as a secondary endpoint for clinical trials in Alzheimer's disease

Authors
Sarah Abbas, Pamela C L Ferreira, Bruna Bellaver, Guilherme Povala, Francieli Rohden, Cristiano Schaffer Aguzzoli, Hussein Zalzale, João Pedro Ferrari-Souza, Douglas T Leffa, Firoza Z Lussier, Carolina Soares, Guilherme Bauer-Negrini, Markley Silva Oliveira-Junior, Matheus Scarpatto Rodrigues, Pampa Saha, Emma Ruppert, Marina Scop Medeiros, Cécile Tissot, Joseph Therriault, Nesrine Rahmouni, Stijn Servaes, Andrea L Benedet, Nicholas J Ashton, Dana L Tudorascu, Serge Gauthier, Helmet Karim, Chang Hyung Hong, Hyun Woong Roh, Eduardo R Zimmer, Thomas K Karikari, Henrik Zetterberg, Kaj Blennow, Anum Saeed, Sang Joon Son, Pedro Rosa-Neto, Tharick Pascoal, for Alzheimer’s Disease Neuroimaging Initiative
Utility of plasma GFAP as a secondary endpoint for clinical trials in Alzheimer's disease
Nature neuroscience
Published

Author Correction: Somatostatin neurons in prefrontal cortex initiate sleep-preparatory behavior and sleep via the preoptic and lateral hypothalamus

Authors
Kyoko Tossell, Xiao Yu, Panagiotis Giannos, Berta Anuncibay Soto, Mathieu Nollet, Raquel Yustos, Giulia Miracca, Mikal Vicente, Andawei Miao, Bryan Hsieh, Ying Ma, Alexei L Vyssotski, Tim Constandinou, Nicholas P Franks, William Wisden
Author Correction: Somatostatin neurons in prefrontal cortex initiate sleep-preparatory behavior and sleep via the preoptic and lateral hypothalamus
Alzheimer's & dementia : the journal of the Alzheimer's Association
Published

LC-MS/MS proteomics identifies plasma proteins related to cognition over 9-year follow-up

Authors
Hailey A Adegboye, Khiry L Patterson, Julia Libby, Yunyi Sun, Panpan Zhang, Dandan Liu, W Hudson Robb, Amalia J Peterson, Keith R Cole, Albert B Arul, Nekesa C Oliver, Marsalas D Whitaker, Kimberly R Pechman, Logan Dumitrescu, Corey J Bolton, Kaj Blennow, Henrik Zetterberg, Timothy J Hohman, Renã A S Robinson, Angela L Jefferson
LC-MS/MS proteomics identifies plasma proteins related to cognition over 9-year follow-up